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SWELL1 Chloride Channel

Cell Volume Regulation and Beyound

Molecular Biology and Physiology of Ion Transport

Chloride is the most abundant free negatively charged ion in the body. Chloride channels are cell-membrane embedded proteins, allowing the movement of chloride in and out of the cells. Defects in chloride fluxes are responsible for many human disorders, including cystic fibrosis, one of the most common genetic disease. However, we know little about some of these mysterious gate-keepers. The Qiu Lab employs a multi-disciplinary approach including high-throughput functional genomics, cell and brain slice electrophysiology, biochemistry, and mouse genetics to discover novel ion channels, elucidate their physiological role, and aim to target them in diseases, including ischemic stroke, epilepsy and glioma.

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Qiu Lab

The Qiu Lab aims to foster a collegial and collaborative environment with a strong focus on mentoring. We are committed to a diverse and inclusive environment where all undergraduate, graduate students and postdocs can thrive and enjoy their learning opportunities as they pursue rigorous scientific research in physiology and neuroscience. 

News

November 2022

Junhua, Kevin and Zhaozhu go to San Diego for SFN 2022 and Patapoutian Lab Reunion

November 2022

Jiachen, Henry, Nick, Martin, and Zhaozhu go to NYC for Ion Channel Modulation Symposium

November 2022

Jianan leaves lab and becomes a professor at Zhengzhou University, best wishes!

October 2022

James and Ljubica post their papers at bioRXiv

July 2022

James' pH sensing paper published at PNAS

 

January 2022

Junhua wins American Heart Association (AHA) Career Development Award and NARSAD Young Investigator Award

 

December 2021

Ljubica wins the Biophysical Society (BPS) Travel Award

December 2021

Henry passes Oral Exam and becomes a PhD candidate

September 2021

James finishes his PhD and moves to Harvard Medical School

Check out our new papers on SWELL1 in glia-neuron interaction in Neuron, and on the discovery, structures, and cellular function of a brand new PAC Proton-Activated Chloride channel in Science, Nature, and Cell Reports!

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