Molecular Biology and Physiology of Ion Transport
Chloride is the most abundant free negatively charged ion in the body. Chloride channels are cell-membrane embedded proteins, allowing the movement of chloride in and out of the cells. Defects in chloride fluxes are responsible for many human disorders, including cystic fibrosis, one of the most common genetic disease. However, we know little about some of these mysterious gate-keepers. The Qiu Lab employs a multi-disciplinary approach including high-throughput functional genomics, cell and brain slice electrophysiology, biochemistry, and mouse genetics to discover novel ion channels, elucidate their physiological role, and aim to target them in diseases, including ischemic stroke, neurodegeneration, and cancer.
Qiu Lab
The Qiu Lab aims to foster a collegial and collaborative environment with a strong focus on mentoring. We are committed to a diverse and inclusive environment where all undergraduate, graduate students and postdocs can thrive and enjoy their learning opportunities as they pursue rigorous scientific research in physiology and neuroscience.
News
January 2023
Junhua's paper published in Neuron, James and Ljubica published their thesis work in two eLife papers, great job!
January 2023
Jiachen finishes her PhD and moves to Seattle as a Consultant, congratulations!
December 2022
Ljubica finishes her PhD and moves to David baker Lab at U Washington, good luck with postdoc research!
November 2022
Junhua, Kevin and Zhaozhu go to San Diego for SFN 2022 and Patapoutian Lab Reunion
November 2022
Jiachen, Henry, Nick, Martin, and Zhaozhu go to NYC for Ion Channel Modulation Symposium
November 2022
Jianan leaves lab and becomes a professor at Zhengzhou University, best wishes!
October 2022
James and Ljubica post their papers at bioRXiv
July 2022
James' pH sensing paper published at PNAS
January 2022
Junhua wins American Heart Association (AHA) Career Development Award and NARSAD Young Investigator Award
December 2021
Ljubica wins the Biophysical Society (BPS) Travel Award
December 2021
Henry passes Oral Exam and becomes a PhD candidate
September 2021
James finishes his PhD and moves to Harvard Medical School
Check out our recent papers on SWELL1 in glia-neuron interaction in Neuron, and on the discovery, structures, regulation, and cellular function of a brand new PAC Proton-Activated Chloride channel in Science, Nature, PNAS, and Cell Reports!